Guest S S, Kirsch C M, Baxter R, Sorooshian M, Young J
Renal Division, Santa Clara Valley Medical Center, San Jose, CA 95128, USA.
Am J Kidney Dis. 1995 Aug;26(2):377-80. doi: 10.1016/0272-6386(95)90661-4.
Endovascular stent placement to prevent restenosis after angioplasty is being increasingly employed. A 63-year-old hemodialysis patient with a right forearm gortex graft developed ipsilateral arm edema, and a right subclavian vein stenosis was diagnosed. This vascular stenosis was presumably secondary to previous placement of temporary access catheters. The subclavian vein stenosis was treated with angioplasty, endovascular stenting, and warfarin, which resulted in resolution of the arm edema. Three weeks after stenting, the patient developed fever to 104 degrees F, chills, and right arm and shoulder edema. All blood cultures grew Staphylococcus aureus, and an Indium-labeled white blood cell scan was positive at the sight of the subclavian stent. Infectious disease consultants recommended urgent removal of the infected stent, but the extensive surgery required posed considerable risk of major morbidity. We elected to conservatively treat the patient. With loss of all upper-extremity access sites, the patient was converted to peritoneal dialysis. Despite the patient's ambulatory status, a femoral venous Hickman catheter was placed and tunneled through the abdominal subcutaneous soft tissue. The patient received 9 weeks of antibiotics by the Hickman catheter with an infusion pump, and warfarin was continued. There has been complete clinical resolution of infection and subclavian thrombosis. Endovascular stents are being used more commonly, and this is the first description, to our knowledge, of a stent infection. The stent infection was successfully managed without surgical removal.
血管内支架置入术用于预防血管成形术后再狭窄的应用越来越广泛。一名63岁的血液透析患者,其右前臂人工血管移植物出现同侧手臂水肿,诊断为右锁骨下静脉狭窄。这种血管狭窄可能继发于先前放置的临时血管通路导管。对锁骨下静脉狭窄进行了血管成形术、血管内支架置入术并使用了华法林,手臂水肿得以消退。支架置入三周后,患者出现发热至104华氏度、寒战以及右臂和肩部水肿。所有血培养均培养出金黄色葡萄球菌,铟标记白细胞扫描显示锁骨下支架部位呈阳性。感染病会诊医生建议紧急取出感染的支架,但所需的广泛手术带来了相当大的严重并发症风险。我们选择对患者进行保守治疗。由于所有上肢血管通路部位均丧失功能,患者改为腹膜透析。尽管患者可自由活动,但仍置入了一根股静脉希克曼导管,并使其通过腹部皮下软组织形成隧道。患者通过希克曼导管使用输液泵接受了9周的抗生素治疗,并继续使用华法林。感染和锁骨下血栓形成已完全临床治愈。血管内支架的使用越来越普遍,据我们所知,这是首例关于支架感染的描述。该支架感染未通过手术取出而成功得到处理。