Maurice N, Crampette L, Mondain M, Guerrier B
Service d'Oto-rhino-laryngologie, Hôpital St-Charles, Montpellier.
Ann Otolaryngol Chir Cervicofac. 1994;111(8):435-42.
Forty-three patients underwent a subtotal laryngectomy with cricohyoidopexy and neck dissection. The 5 years overall survival rate was 67%, the actuarial survival rate was 75%. The 5-year actuarial local control and nodal control rate were namely 89% and 90%. Pronostic factors for survival were tumor size (5-year actuarial survival rate for T2a, T2b and T3 were namely 89%, 72%, 48%) and node involvement (5 years actuarial survival rate was 85% if N-, and 46% if N+). The median duration was 22 days for decanulation, 30 days for removing the feeding tube. The median hospital discharge day was 38. Total laryngectomy was performed in one case (2.3%) for persistent aspiration. Post operative mortality was 0%. The most common complication was aspiration pneumoniae (11.6% of the cases).
43例患者接受了喉次全切除术联合环状软骨舌骨固定术及颈部清扫术。5年总生存率为67%，精算生存率为75%。5年精算局部控制率和淋巴结控制率分别为89%和90%。生存的预后因素为肿瘤大小（T2a、T2b和T3的5年精算生存率分别为89%、72%、48%）和淋巴结受累情况（N-时5年精算生存率为85%，N+时为46%）。拔管的中位时间为22天，拔除鼻饲管的中位时间为30天。中位出院天数为38天。1例（2.3%）因持续性误吸行全喉切除术。术后死亡率为0%。最常见的并发症是吸入性肺炎（占病例的11.6%）。
