变形链球菌葡糖基转移酶-S的C末端直接重复单元在葡聚糖结合中的作用
Role of C-terminal direct repeating units of the Streptococcus mutans glucosyltransferase-S in glucan binding.
作者信息
Lis M, Shiroza T, Kuramitsu H K
机构信息
Department of Oral Biology, State University of New York, Buffalo 14214, USA.
出版信息
Appl Environ Microbiol. 1995 May;61(5):2040-2. doi: 10.1128/aem.61.5.2040-2042.1995.
Abstract
The C-terminal glucan-binding domain of the glucosyltransferase-S of Streptococcus mutans GS-5 contains five 65-amino-acid direct repeating units. A series of deletion derivatives of both the glucosyltransferase-S and its glucan-binding domain were constructed and analyzed. The results demonstrated that the four C-terminal direct repeating units constituted part of the minimum domain required for glucan binding.
摘要
变形链球菌GS-5的葡糖基转移酶S的C末端葡聚糖结合结构域包含五个65个氨基酸的直接重复单元。构建并分析了葡糖基转移酶S及其葡聚糖结合结构域的一系列缺失衍生物。结果表明，四个C末端直接重复单元构成了葡聚糖结合所需最小结构域的一部分。
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