Chardigny C, Jebara V, Descombes J J, Acar C, Verbeuren T, Fabiani J N
Laboratoire d'études des greffes et prothèses cardiaques, hôpital Broussais, Paris.
Arch Mal Coeur Vaiss. 1994 Sep;87(9):1185-93.
Satisfactory results were obtained with the radial artery used as a conduit for coronary artery bypass. However, spasm of this conduit was observed. Human radial and internal mammary artery ring segments were studied in organ chambers. Potassium chloride, norepinephrine, serotonin and thromboxane A2 mimetic were used to obtain dose-response curves, permitting assessment of force of contraction and sensitivity. The radial artery presents stronger contractions than the internal mammary artery. The two vessels have equal sensitivity to the vasoconstrictors used. These data emphasize the hyperreactivity of the radial artery and the need for prevention of vasospasm when this vessel is used as a conduit for coronary artery bypass.
将桡动脉用作冠状动脉搭桥的血管 conduit 取得了满意的结果。然而，观察到了该血管 conduit 的痉挛。在器官腔室中研究了人桡动脉和乳内动脉环段。使用氯化钾、去甲肾上腺素、血清素和血栓素 A2 模拟物来获得剂量反应曲线，以评估收缩力和敏感性。桡动脉的收缩比乳内动脉更强。这两种血管对所使用的血管收缩剂具有相同的敏感性。这些数据强调了桡动脉的高反应性以及当该血管用作冠状动脉搭桥的血管 conduit 时预防血管痉挛的必要性。
