du Cailar G, Mimran A
Service de médecine interne G, hôpital Lapeyronie, Montpellier.
Arch Mal Coeur Vaiss. 1995 Feb;88 Spec No 2:15-9.
Dietary sodium is an environmental factor capable of amplifying or limiting the consequences of hypertension on the heart. In a given population of hypertensive subjects, recent clinical trials have shown a positive relationship between sodium intake and the degree of left ventricular hypertrophy, independently of the value of blood pressure and body weight. In addition, dietary sodium could play a role in modulating the myocardial response to a decrease in blood pressure by antihypertensive therapy. The logical consequence of these observations is to try and prove the possible advantages of restricting dietary sodium in reducing the blood pressure and reversing left ventricular hypertrophy. With this in mind, the evaluation of dietary sodium excretion is certainly an element to take into account in the initial evaluation and also the follow-up of hypertensive subjects and of the effects of antihypertensive therapy.
膳食钠是一种环境因素，能够放大或限制高血压对心脏的影响。在特定的高血压患者群体中，近期的临床试验表明，钠摄入量与左心室肥厚程度之间存在正相关关系，且独立于血压值和体重。此外，膳食钠可能在调节心肌对降压治疗引起的血压下降的反应中发挥作用。这些观察结果的合理推论是尝试证明限制膳食钠在降低血压和逆转左心室肥厚方面可能具有的优势。考虑到这一点，评估膳食钠排泄量无疑是高血压患者初始评估以及后续评估和降压治疗效果评估中需要考虑的一个因素。
