Dunphy C H
Department of Pathology, St Louis University Health Sciences Center, MO, USA.
Arch Pathol Lab Med. 1995 Aug;119(8):757-9.
Patients with acquired immunodeficiency syndrome are at increased risk of developing malignant lymphoma, particularly of the large noncleaved, immunoblastic, and small noncleaved cell types. Angiotropic large-cell lymphoma, a relatively rare high-grade lymphoma, has not previously been described in the setting of acquired immunodeficiency syndrome. Because angiotropic large-cell lymphoma most commonly involves the skin and central nervous system, and because of its relative rarity, its presentation in the skin of a patient with acquired immunodeficiency syndrome may pose a diagnostic dilemma.
获得性免疫缺陷综合征患者发生恶性淋巴瘤的风险增加，尤其是大细胞未分化型、免疫母细胞型和小细胞未分化型。血管中心性大细胞淋巴瘤是一种相对罕见的高级别淋巴瘤，此前尚未在获得性免疫缺陷综合征患者中被描述。由于血管中心性大细胞淋巴瘤最常累及皮肤和中枢神经系统，且因其相对罕见，其在获得性免疫缺陷综合征患者皮肤中的表现可能会造成诊断上的两难局面。
