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[美帕曲星在良性前列腺腺瘤医学治疗中的作用]

[The role of mepartricin in the medical treatment of benign prostatic adenoma].

作者信息

Casella G, Barbaro A

出版信息

Arch Sci Med (Torino). 1978 Jan-Mar;135(1):95-8.

PMID:76466
Abstract

A "cross over" study was carried out in a group of 22 subjects with prostatic hypertrophy in different stages, first treated with chloroformic extract of Pygeum Africanum (4 capsules/die for 30 days) and afterwards, when the symptoms reappeared, with mepartricin (3 gastroresistant tablets of 50,000 U. each/die for 30 days). Both substances proved to be active against the urinary symptomatology; however the polyene induced a significant decrease in the prostate size (evaluated by cystography), justifying the 77% of "excellent" results against the 13% obtained with the reference drug.

摘要

对一组22名处于不同阶段前列腺增生的受试者进行了一项“交叉”研究,首先用非洲臀果木氯仿提取物治疗(每天4粒胶囊,持续30天),之后当症状再次出现时,用美帕曲星治疗(每天3片50000单位的胃溶片,持续30天)。两种物质都被证明对泌尿系统症状有效;然而,多烯类药物使前列腺大小显著减小(通过膀胱造影评估),这使得使用该药物获得“极佳”效果的比例达到77%,而使用参比药物仅为13%。

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