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[寂静性甲状腺炎与产后甲状腺炎]

[Silent thyroiditis and postpartum thyroiditis].

作者信息

Díez J J

机构信息

Servicio de Endocrinología, Hospital La Paz, Madrid.

出版信息

Aten Primaria. 1995 Jul-Aug;16(3):147-50.

PMID:7647209
Abstract

OBJECTIVE

Six cases of silent thyroiditis are described. Clinical, analytical, therapeutical and prognostical features are reviewed.

DESIGN

Descriptive and retrospective study.

SETTING

Outpatient endocrinological clinic of a General Hospital

PATIENTS OR OTHER PARTICIPANTS

Six women (age 26-41 years) that fulfil clinical and analytical criteria of silent thyroiditis. In 4 patients thyroiditis was diagnosed in the postpartum period and in the remaining 2 there was no relationship with pregnancy.

MAIN MEASUREMENTS AND RESULTS

Serum levels of thyroid hormones and thyroglobulin and thyroid peroxidase antibodies were measured in all patients. Follow-up period was between 12 and 41 months. The 2 patients with the sporadic form of silent thyroiditis showed clinical and analytical data of thyrotoxicosis that spontaneously resolved. The remaining 4 patients presented with hypothyroidism. In one of them the hypothyroidism spontaneously resolved, in 2 it became permanent and in a further one it developed to subclinical hypothyroidism.

CONCLUSIONS

Silent thyroiditis (sporadic or postpartum) is a frequent disorder, usually benign and transient. It can present in different clinic forms and evolve to resolution of permanent thyroid dysfunction.

摘要

目的

描述6例寂静性甲状腺炎病例。对其临床、分析、治疗及预后特征进行综述。

设计

描述性回顾性研究。

地点

一家综合医院的门诊内分泌诊所

患者或其他参与者

6名女性(年龄26 - 41岁),符合寂静性甲状腺炎的临床及分析标准。4例患者在产后被诊断为甲状腺炎,其余2例与妊娠无关。

主要测量指标及结果

测定所有患者的血清甲状腺激素、甲状腺球蛋白及甲状腺过氧化物酶抗体水平。随访期为12至41个月。2例散发性寂静性甲状腺炎患者表现出甲状腺毒症的临床及分析数据,且自发缓解。其余4例患者出现甲状腺功能减退。其中1例甲状腺功能减退自发缓解,2例变为永久性,另1例发展为亚临床甲状腺功能减退。

结论

寂静性甲状腺炎(散发性或产后型)是一种常见疾病,通常为良性且短暂性。它可表现为不同的临床形式,并可演变为永久性甲状腺功能障碍的缓解。

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