Irie T, Yamauchi T, Makita K, Kusano S
Department of Radiology, National Defense Medical College, Saitama, Japan.
J Vasc Interv Radiol. 1995 May-Jun;6(3):449-54. doi: 10.1016/s1051-0443(95)72840-8.
To develop an inferior vena cava (IVC) filter that is retrievable even after neointimal formation and incorporation into the caval wall.
Eight filters were placed percutaneously in the infrarenal IVC of eight dogs. Four weeks after placement, percutaneous retrieval of the filters was attempted. Vena cavograms were obtained before and immediately after retrieval. Three dogs were killed immediately after the retrieval procedure was completed. In the other five dogs, follow-up vena cavography was performed 4-14 weeks after retrieval, and autopsy was performed.
The filters were placed and retrieved successfully in all eight dogs. No migration, caval penetration, or tilting occurred. The IVCs were completely patent both before and immediately after retrieval in all eight dogs. In the three dogs killed immediately after retrieval, neointimal hyperplasia was seen around the struts, but there was no detachment. Delayed stenosis was not seen in any of the five dogs that were followed up, and the inner surface of the caval wall was smooth.
This IVC filter can be easily placed and safely retrieved percutaneously, even after neointimal formation.
研发一种下腔静脉（IVC）滤器，即使在新生内膜形成并融入腔壁后仍可取出。
在8只犬的肾下腔静脉经皮置入8个滤器。置入4周后，尝试经皮取出滤器。在取出前及取出后立即进行腔静脉造影。在取出操作完成后，立即处死3只犬。在另外5只犬中，取出后4 - 14周进行随访腔静脉造影，并进行尸检。
所有8只犬的滤器均成功置入并取出。未发生移位、腔静脉穿孔或倾斜。所有8只犬在取出前及取出后立即腔静脉均完全通畅。在取出后立即处死的3只犬中，在支柱周围可见新生内膜增生，但未发生脱落。在随访的5只犬中均未见到延迟性狭窄，腔壁内表面光滑。
这种IVC滤器即使在新生内膜形成后也可经皮轻松置入并安全取出。
