Emeryk A, Jedrych M, Górnicka G, Czerwińska I, Jaworowska J
Kliniki Chorób Dzieci Młodszych Instytutu Pediatrii AM w Lublinie.
Pneumonol Alergol Pol. 1995;63(3-4):197-200.
The study was conducted on 474 children diagnosed at the Lung Function Laboratory of the Children' Hospital in Lublin in the year 1992. 55% of the analyzed children were males. The children's initial diagnosis were: bronchial asthma, allergic rhinitis, chronic respiratory disorders, diabetes mellitus, abnormalities of the thorax. In 28 children no abnormalities were detected. PEF was measured with a Peak Flow Meter produced by Vitalograph. Children in the age group 4-6 years had PEF measured with a mini meter, reading values between 0 to 300 L/min. A standard meter was used for older children detecting values between 0 to 700 L/min. Spirometry, MEFV curves, resistance were analyzed with the abcPNEUMO 2000 spirometer (abcMED). Correlation was calculated between PEF and FEV1, MEF25, MEF50, MEF75, PEF, PIF, FEV1%FVC, Raw. Multiple regression analysis was performed to identify the best subpopulation of independent variants. In all children a correlation was found between PEF and the major parameters of airways potency. The weakest correlation was found in children younger than 6 years. PEF correlated best with FEV1 and MEF75.
该研究针对1992年在卢布林儿童医院肺功能实验室确诊的474名儿童开展。所分析儿童中55%为男性。儿童的初始诊断包括:支气管哮喘、过敏性鼻炎、慢性呼吸道疾病、糖尿病、胸廓异常。28名儿童未检测到异常。使用维托拉夫公司生产的峰值流量计测量呼气峰流速(PEF)。4至6岁年龄组的儿童使用小型流量计测量PEF,读数范围为0至300升/分钟。年龄较大的儿童使用标准流量计,检测值范围为0至700升/分钟。使用abcPNEUMO 2000肺功能仪(abcMED)分析肺量计、最大呼气流量容积(MEFV)曲线、阻力。计算PEF与第一秒用力呼气容积(FEV1)、最大呼气流量25%(MEF25)、最大呼气流量50%(MEF50)、最大呼气流量75%(MEF75)、PEF、吸气峰流速(PIF)、FEV1占用力肺活量百分比(FEV1%FVC)、气道阻力(Raw)之间的相关性。进行多元回归分析以确定最佳的独立变量亚组。在所有儿童中,均发现PEF与气道效能的主要参数之间存在相关性。在6岁以下儿童中发现的相关性最弱。PEF与FEV1和MEF75的相关性最佳。