Weinberger M, Eid A, Schreiber L, Shapiro M, Ilan Y, Libson E, Sacks T, Tur-Kaspa R
Department of Internal Medicine C and Infectious Diseases, Belinson Medical Centre, Petah Tiqwa, Israel.
Eur J Clin Microbiol Infect Dis. 1995 Apr;14(4):337-41. doi: 10.1007/BF02116527.
Infections due to Nocardia transvalensis are extremely rare: only four disseminated infections with this pathogen have been reported, three of which ended fatally. This is the first report of a liver transplant recipient with Nocardia transvalensis infection. The patient had disseminated infection with pulmonary involvement, which presented as pulmonary infarction. Despite a ten-day delay in the administration of correct therapy, he responded rapidly to trimethoprim-sulfamethoxazole. The pitfalls of differentiating nocardial infection from pulmonary thromboembolism in solid organ transplant recipients and the diagnostic considerations unique to liver transplant recipients are discussed.
仅报告过4例由该病原体引起的播散性感染,其中3例死亡。这是首例肝移植受者发生超越瓦利诺卡菌感染的报告。该患者发生了伴有肺部受累的播散性感染,表现为肺梗死。尽管在给予正确治疗方面延迟了10天,但他对甲氧苄啶-磺胺甲恶唑反应迅速。文中讨论了实体器官移植受者中诺卡菌感染与肺血栓栓塞鉴别诊断的陷阱以及肝移植受者特有的诊断考量。