Burris J F
Department of Medicine, Georgetown University Medical Center, Washington, DC, USA.
J Clin Pharmacol. 1995 Apr;35(4):337-42. doi: 10.1002/j.1552-4604.1995.tb04070.x.
Angiotensin converting enzyme (ACE) inhibitors are increasingly important in antihypertensive therapy because of their efficacy, tolerability, and specific benefits in subsets of patients. They are pharmacologically diverse. Whereas most benefits have been proven with older agents (captopril, enalopril), newer agents, such as benazepril, quinapril, and ramipril, offer potential advantages that remain to be proven.
由于血管紧张素转换酶（ACE）抑制剂在降压治疗中的疗效、耐受性以及对特定患者亚组的特殊益处，其在降压治疗中的重要性日益凸显。它们在药理作用上具有多样性。虽然大多数益处已在老一代药物（卡托普利、依那普利）中得到证实，但新一代药物，如贝那普利、喹那普利和雷米普利，具有一些尚待证实的潜在优势。
