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[血栓形成的简化门诊治疗。皮下注射低分子量肝素的每日剂量]

[Simplified ambulatory treatment of thrombosis. A daily dosage of subcutaneous low-molecular-weight heparin].

作者信息

Hallert C, Blomqvist K

机构信息

Medicinkliniken, Lasarettet i Norrköping.

出版信息

Lakartidningen. 1995 Aug 23;92(34):3011-3.

PMID:7650990
Abstract

Of 162 patients aged 27-28 years, referred during a 12-month period to the Dept. of medicine, Norrköping Central Hospital, for deep vein thrombosis (DVT), 102 (63 per cent) were treated as out-patients with the low molecular weight heparin preparation, dalteparin (Fragmin), given subcutaneously at a standardised daily dosage of 200 U/kg. No serious thrombotic events were reported. The frequency of post-thrombotic symptoms at six months did not differ from that among hospitalised patients on standard heparin treatment. Thus, the proportion of DVT patients treated as in-patients was reduced by 50 per cent, despite a 33 per cent increase in the number of referrals for DVT during the period. At follow-up, almost 90 per cent of the patients expressed satisfaction with the out-patient routines.

摘要

在12个月期间,162名年龄在27至28岁之间、因深静脉血栓形成(DVT)转诊至诺尔雪平中央医院内科的患者中,102名(63%)作为门诊患者接受治疗,使用低分子量肝素制剂达肝素(法安明),以200 U/kg的标准化日剂量皮下注射。未报告严重血栓事件。六个月时血栓形成后症状的发生率与接受标准肝素治疗的住院患者无差异。因此,尽管在此期间DVT转诊患者数量增加了33%,但作为住院患者治疗的DVT患者比例减少了50%。在随访中,近90%的患者对门诊程序表示满意。

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