Voigtländer T, Nowak B, Treese N, Poschmann G, Becker H J, Meyer J
II. Medizinische Klinik und Poliklinik, Johannes-Gutenberg-Universaität Mainz.
Z Kardiol. 1995 Jun;84(6):459-67.
VDD stimulation is an alternative to DDD pacing due to the possibility of p-wave synchronous ventricular pacing without the need of an atrial lead. Mainly, the reliability of the system depends on the atrial sensing. In 22 patients the intraoperative atrial amplitude and, postoperatively, the atrial sensing threshold were measured. Furthermore, the stability of the atrial sensing threshold during follow-up was proven. The mean atrial amplitude was intraoperative by 2.4 +/- 1.2 (1.0-6.8) mV. The measurement of the atrial sensing threshold in the first 5 postoperative days showed a mean value of 1.02 +/- 0.49 (0.3-1.6) mV. The measurements of the mean atrial sensing threshold after 30, 90, and 180 days showed no statistical differences. Intraindividual variance was shown in 17/20 patients (0.55 +/- 0,42; 0.15-1.05 mV). Seventeen of the 22 patients were programmed with an atrial sensing threshold of 0.3 mV. In five patients the atrial sensing threshold was programmed at less than 0.3 mV in order to reach a twofold atrial sensitivity. Despite a programmed atrial sensitivity of 0.1 mV and isometric conditions no atrial oversensing occurred. The postoperative atrial sensing thresholds of the VDD system investigated were significantly lower than the intraoperatively measured atrial amplitudes. The mean atrial sensing threshold did not change during the follow-up period. The variation which did occur was within individual variation at different return visits.
由于VDD刺激有可能实现P波同步心室起搏且无需心房电极,因此它是DDD起搏的一种替代方案。该系统的可靠性主要取决于心房感知。对22例患者术中测量了心房振幅,术后测量了心房感知阈值。此外,还证实了随访期间心房感知阈值的稳定性。术中平均心房振幅为2.4±1.2(1.0 - 6.8)mV。术后前5天测量的心房感知阈值平均值为1.02±0.49(0.3 - 1.6)mV。术后30天、90天和180天测量的平均心房感知阈值无统计学差异。20例患者中有17例(0.55±0.42;0.15 - 1.05 mV)存在个体差异。22例患者中有l7例将心房感知阈值设定为mV。5例患者的心房感知阈值设定低于0.3 mV,以达到两倍的心房敏感性。尽管设定的心房敏感性为0.1 mV且处于等长条件下,但未发生心房过感知。所研究的VDD系统术后心房感知阈值显著低于术中测量的心房振幅。随访期间平均心房感知阈值未发生变化。所发生的变化在不同复诊时的个体差异范围内。