Toxoplasmosis: antitoxoplasma IgG antibody levels in patients with lymphoid neoplasia in Ibadan, Nigeria.

The serum samples of 50 patients with lymphoid neoplasia, and of 112 control subjects from the normal population were analysed for the presence of antitoxoplasma IgG antibodies by the enzyme-linked immunosorbent assay technique. There was no significant difference between the prevalence rate of antitoxoplasma IgG antibodies in the control subjects (69%) and the patients with lymphoid neoplasia (66%). The prevalence of antitoxoplasma IgG antibody levels of 75 international units (i.u.) per ml and above was significantly higher in the patients (48%) than in the control subjects (18%). Antitoxoplasma IgG antibody levels of 150 i.u. and above per ml indicating active toxoplasmosis were present in 13 (26%) out of the 50 patients with lymphoid neoplasia. None of the sera from the control subjects had antitoxoplasma IgG antibody level up to 150 i.u. per ml of serum.