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[血液缓慢流动膜氧合作为腹部脓毒症患者治疗中解毒的一种方法]

[Slow-flow membrane oxygenation of blood as a method of detoxication in the treatment of patients with abdominal sepsis].

作者信息

Lobakov A I, Vatazin A V, Vasin Iu V, Drozdova G A, Karichev Z R

出版信息

Anesteziol Reanimatol. 1995 May-Jun(3):39-40.

PMID:7653863
Abstract

The criteria of efficacy of small-flow membranous oxygenation of the blood were defined and the duration of this measure optimized in the treatment of 30 patients hospitalized at the department for abdominal surgery, Moscow District Research and Clinical Institute, after operations for abdominal diseases and purulent complications thereof performed at hospitals of the Moscow district. Small-flow membranous oxygenation of the blood brought about a trend to normalization of the peripheral blood parameters which were changed as a result of inflammation; it was conducive to normalization of the blood acid-base status and oxygen extraction by tissues, and had an immunostimulating effect in general. The level of medium-weight molecular peptides may be regarded as a criterion of the efficacy of small-flow membranous oxygenation of the blood. With an initial concentration of medium-weight molecules of at least 1 arbitrary unit, the procedure may be as short as just two hours. Under such conditions, small-flow membranous oxygenation of the blood may be considered as a specific detoxifying method.

摘要

确定了小流量膜式血液氧合的疗效标准,并对在莫斯科地区研究与临床研究所腹部外科住院的30例患者进行了优化,这些患者在莫斯科地区医院接受了腹部疾病手术及其化脓性并发症手术后。小流量膜式血液氧合使因炎症而改变的外周血参数有趋于正常化的趋势;有利于血液酸碱状态和组织氧提取的正常化,总体上具有免疫刺激作用。中等分子量肽的水平可被视为小流量膜式血液氧合疗效的标准。当初始中等分子量分子浓度至少为1个任意单位时,该过程可能短至仅两小时。在这种情况下,小流量膜式血液氧合可被视为一种特定的解毒方法。

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