Chmielewski C M
ANNA J. 1995 Aug;22(4):420-3.
Erythrokinetics is a physiologic process that regulates red blood cell dynamics. In keeping with the present trend of focusing on patient outcomes and costs, an erythrokinetic model provides a guideline for appropriate dosing of Epoetin alfa to maintain a hematocrit within the target range of 30% to 36%. Maintaining the patient's hematocrit at the optimal level influences patient outcomes by enhancing the quality of life and improving patient management by decreasing time and costs.
红细胞动力学是调节红细胞动态变化的生理过程。为顺应目前关注患者预后和成本的趋势,红细胞动力学模型可为适当剂量的促红细胞生成素α提供指导,以将血细胞比容维持在30%至36%的目标范围内。将患者的血细胞比容维持在最佳水平可通过提高生活质量和减少时间及成本来改善患者管理,从而影响患者预后。