Smith W P, Markus A F, Delaire J
Maxillofacial Unit, Poole Hospital NHS Trust, Dorset.
Br J Oral Maxillofac Surg. 1995 Jun;33(3):156-65. doi: 10.1016/0266-4356(95)90289-9.
The growth and development of the premaxilla in both normal and cleft lip and palate subjects is described and its relevance in surgery of the cleft alveolus discussed. Embryologically, the cleft alveolus results from failure of fusion of the median nasal and maxillary processes. Consequently, ossification centres in the premaxilla and maxilla cannot migrate and unite such that normal growth and development in the territory of the premaxillary-maxillary suture cannot occur. Functional repair of the cleft lip and soft palate encourages spontaneous alignment of the alveolar segments, facilitating the introduction of vascularized periosteum across the bony defect by gingivoperiosteoplasty. Early reconstruction in the region of the premaxillary-maxillary suture encourages a more normal development of the alveolus, particularly in the bilateral cleft subject.
描述了正常以及唇腭裂患者前颌骨的生长发育情况,并讨论了其在牙槽裂手术中的相关性。从胚胎学角度来看,牙槽裂是由于正中鼻突与上颌突融合失败所致。因此,前颌骨和上颌骨的骨化中心无法迁移并融合,导致前颌-上颌缝区域无法正常生长发育。唇裂和软腭裂的功能性修复可促使牙槽突自发对齐,便于通过牙龈骨膜成形术将带血管的骨膜引入骨缺损处。在前颌-上颌缝区域进行早期重建有助于牙槽突更正常地发育,尤其是对于双侧唇腭裂患者。