Meyers C A, Weitzner M A
Department of Neuro-oncology, University of Texas MD Anderson Cancer Center, Houston 77030, USA.
Curr Opin Oncol. 1995 May;7(3):197-200. doi: 10.1097/00001622-199505000-00001.
There are relatively few studies that systematically address the cognitive and emotional functioning of brain tumor patients. Several conclusions, however, can be made from these studies. First, performance status measures and neurologic examinations do not adequately address cognitive functioning and quality of life in these patients. Second, global measures of cognitive functioning such as IQ scores can be relatively insensitive, and tests of specific cognitive functions need to be performed. There will soon be an increasing focus on neurobehavioral functioning and quality of life in new therapeutic trials as the simple reporting of survival becomes an increasingly inadequate outcome measure. In addition, the information gained from neurobehavioral and quality of life studies will be used to guide intervention techniques to improve the functioning of the survivors of brain tumors.
系统探讨脑肿瘤患者认知与情感功能的研究相对较少。然而，从这些研究中可以得出几个结论。首先，性能状态测量和神经学检查并不能充分评估这些患者的认知功能和生活质量。其次，诸如智商分数等认知功能的整体测量可能相对不敏感，需要进行特定认知功能的测试。随着单纯的生存报告越来越不足以作为结果衡量指标，新的治疗试验将很快越来越关注神经行为功能和生活质量。此外，从神经行为和生活质量研究中获得的信息将用于指导干预技术，以改善脑肿瘤幸存者的功能。
