Barrett S F, Wright C H, Jerath M R, Lewis R S, Dillard B C, Rylander H G, Welch A J
Department of Electrical Engineering, USAF Academy, CO 80840, USA.
Biomed Sci Instrum. 1995;31:89-93. doi: 10.1117/12.208403.
Researchers at the University of Texas and the USAF Academy have worked toward the development of a retinal robotic laser system. The overall goal of this ongoing project is to precisely place and control the depth of laser lesions for the treatment of various retinal diseases such as diabetic retinopathy and retinal tears. Separate low speed prototype subsystems have been developed to control lesion depth using lesion reflectance feedback parameters and lesion placement using retinal vessels as tracking landmarks. Both subsystems have been successfully demonstrated in vivo on pigmented rabbits using an argon continuous wave laser. Recent efforts have concentrated on combining the two subsystems into a single prototype capable of simultaneously controlling both lesion depth and placement. We have designated this combined system CALOSOS for Computer Aided Laser Optics System for Ophthalmic Surgery. Following the dual-use concept, this system is being adapted for clinical use as a retinal treatment system as well as a research tool for military laser-tissue interaction studies.
德克萨斯大学和美国空军学院的研究人员一直致力于开发一种视网膜机器人激光系统。这个正在进行的项目的总体目标是精确地定位和控制激光损伤的深度,以治疗各种视网膜疾病,如糖尿病性视网膜病变和视网膜裂孔。已经开发了单独的低速原型子系统,以利用损伤反射率反馈参数控制损伤深度,并以视网膜血管作为跟踪标志来控制损伤位置。这两个子系统都已在色素兔体内使用氩连续波激光成功进行了演示。最近的工作集中在将这两个子系统组合成一个能够同时控制损伤深度和位置的单一原型。我们将这个组合系统命名为CALOSOS,即眼科手术计算机辅助激光光学系统。遵循两用概念,该系统正在被改造成临床用视网膜治疗系统以及军事激光与组织相互作用研究的研究工具。