Donker D N, Njio L, van Leeuwen W S, Wieneke G
Electroencephalogr Clin Neurophysiol. 1978 Apr;44(4):479-89. doi: 10.1016/0013-4694(78)90032-9.
(1) The interhemispheric amplitude correlations of the fundamental (A1) and second harmonic (A2) components of responses to sine wave modulated light were determined in the occipital, parietal and temporal scalp areas of a group of normal subjects and a group of patients with unilateral irritative EEG phenomena. The interhemispheric amplitude correlation was computed at 10- and 16-c/sec stimulation frequencies and under 3 conditions: no modulation and no attention (M-, A-), modulation 30%, and no attention (M+, A-) and modulation 30% and attention (M+, A+). The correlations wre expressed in the rank correlation coefficient of Kendall (rK). (2) Analysis of variance revealed that the interhemispheric amplitude correlation of A1 in the normal group was significantly larger than that in the patient group at a stimulation frequency of 10 c/sec and under the conditions (M-, A-) and (M+, A-). (3) Both groups presented the largest correlation coefficients in the occipital scalp area. (4) In the normal group a significant increase of rK occurred under the influence of modulation. Attention caused a decrease of the correlation coefficient of A1. In the group of patients this influence was not clear. (5) The standard deviation of the mean interhemispheric phase differences was considered as a measure of synchrony of the response components between the two hemispheres. The smallest values of standard deviation were found in the occipital scalp area of the normal group at 10 c/sec stimulation frequency. Considerable variations between individuals were observed in both groups. (6) The correlation between the interhemispheric amplitude correlation (rK) and the interhemispheric synchrony was influenced by changing modulation depth from 0 to 30% and by introduction of attention, mostly in the group of normal subjects. This phenomenon was considered to support the theory that in patients with unilateral EEG disturbances the interhemispheric relations are different from those in normal subjects. (7) The findings as to amplitude correlation (rK) were the same under the condition (M-, A-) as under the condition (M+, A-).
(1) 在一组正常受试者和一组有单侧刺激性脑电图现象的患者的枕部、顶叶和颞部头皮区域，测定了对正弦波调制光反应的基波（A1）和二次谐波（A2）成分的半球间振幅相关性。在10和16赫兹的刺激频率下，以及在3种条件下计算半球间振幅相关性：无调制且无注意力（M-，A-）、30%调制且无注意力（M+，A-）和30%调制且有注意力（M+，A+）。相关性用肯德尔等级相关系数（rK）表示。(2) 方差分析显示，在10赫兹的刺激频率下，以及在（M-，A-）和（M+，A-）条件下，正常组A1的半球间振幅相关性显著大于患者组。(3) 两组在枕部头皮区域呈现出最大的相关系数。(4) 在正常组中，调制的影响下rK显著增加。注意力导致A1相关系数降低。在患者组中，这种影响不明显。(5) 平均半球间相位差的标准差被视为两个半球反应成分同步性的指标。在10赫兹刺激频率下，正常组枕部头皮区域的标准差最小值被发现。两组个体间均观察到相当大的差异。(6) 半球间振幅相关性（rK）与半球间同步性之间的相关性受调制深度从0%变化到30%以及注意力引入的影响，主要在正常受试者组中。这种现象被认为支持了这样一种理论，即单侧脑电图干扰患者的半球间关系与正常受试者不同。(7) 在（M-，A-）条件下和（M+，A-）条件下，关于振幅相关性（rK）的发现是相同的。
