Fischer M, Hoffmann U, Oomen P, Herrig I, Franzeck U K, Bollinger A
Department of Medicine, University Hospital, Zürich, Switzerland.
Eur J Vasc Endovasc Surg. 1995 Aug;10(2):231-6. doi: 10.1016/s1078-5884(05)80118-2.
To assess feasibility of a new technique for simultaneous measurement of digital artery and skin perfusion pressure at the same digit using the laser Doppler method and to measure the pressure gradient between the two vessel compartments in controls and patients with peripheral arterial occlusive disease.
A pressure cuff wrapped around the basis of the toe and connected to a Statham transducer is covered by a special plastic capsule. A hole at the distal end of the capsule permits positioning of a laser Doppler probe at the pulp. A second laser Doppler probe is placed on the skin beneath the pressure cuff. Reappearance of pulsatile flux during cuff pressure release detected by the two laser Doppler probes indicated digital artery pressure and skin perfusion pressure on the corresponding pressure curve. Results in patients with intermittent claudication were compared to results of a group of normal controls.
University Hospital, Zürich, Switzerland.
Eleven healthy volunteers and 14 patients with intermittent claudication due to peripheral arterial occlusive disease were studied.
Digital artery pressure (DAP), skin perfusion pressure (SPP) and pressure gradient between DAP and SPP.
Significantly lower mean DAP (95.8 +/- 23.2 mmHg vs. 49.8 +/- 20.4 mmHg; p < 0.01) and mean SPP (81.4 +/- 18.8 mmHg vs. 38.4 +/- 21.7 mmHg; p < 0.01) were observed in the patients. Mean pressure gradients and ratios between DAP and SPP did not differ significantly between the two groups. There was a linear correlation between DAP and SPP (r = 0.82, p < 0.01).
The laser Doppler method provides the possibility to measure digital artery and skin perfusion pressure simultaneously at the same digit in an easy and non-invasive way. Pressure gradients between DAP and SPP are similar in controls and patients with claudication.
评估一种使用激光多普勒方法同时测量同一手指的指动脉和皮肤灌注压的新技术的可行性，并测量对照组和外周动脉闭塞性疾病患者两个血管腔室之间的压力梯度。
一个包裹在脚趾根部并连接到斯塔瑟姆换能器的压力袖带被一个特殊的塑料胶囊覆盖。胶囊远端的一个孔允许将激光多普勒探头放置在指腹处。第二个激光多普勒探头放置在压力袖带下方的皮肤上。两个激光多普勒探头在袖带压力释放期间检测到的搏动性通量的重现表明了相应压力曲线上的指动脉压和皮肤灌注压。将间歇性跛行患者的结果与一组正常对照组的结果进行比较。
瑞士苏黎世大学医院。
研究了11名健康志愿者和14名因外周动脉闭塞性疾病导致间歇性跛行的患者。
指动脉压（DAP）、皮肤灌注压（SPP）以及DAP和SPP之间的压力梯度。
在患者中观察到平均DAP（95.8±23.2 mmHg对49.8±20.4 mmHg；p<0.01）和平均SPP（81.4±18.8 mmHg对38.4±21.7 mmHg；p<0.01）显著降低。两组之间DAP和SPP的平均压力梯度和比值没有显著差异。DAP和SPP之间存在线性相关性（r = 0.82，p<0.01）。
激光多普勒方法提供了一种以简单且无创的方式同时测量同一手指的指动脉和皮肤灌注压的可能性。对照组和跛行患者中DAP和SPP之间的压力梯度相似。
