Guo H, Li S, Cao X
Department of Ophthalmology, Second Teaching Hospital, Guangzhou Medical College.
Zhonghua Yan Ke Za Zhi. 1995 Mar;31(2):102-4.
The cultures of human lens epithelial cells taken from both normal and cataractous lenses were established in vitro. The biological characteristics and the histological changes of the cells were investigated. 5-Fluorouracil (5-Fu), Homoharring tonine (HH) and Harmeline (H) were used for the inhibition of the proliferative cells in the experiment. The results revealed that the in vitro survival capacity of the human lens epithelial cells is limited and the proliferative capacity of the cells is negatively correlated to the donor age. HH and H can effectively inhibit the lens epithelial cell proliferation. Based on the results of this report, performing small and smoothly edged anterior capsulorhexis in extracapsular cataract extraction may possibly decrease the incidence of the post-operative opacification of the posterior capsule.
建立了从正常晶状体和白内障晶状体获取的人晶状体上皮细胞的体外培养体系。对这些细胞的生物学特性和组织学变化进行了研究。实验中使用5-氟尿嘧啶（5-Fu）、高三尖杉酯碱（HH）和骆驼蓬碱（H）来抑制增殖细胞。结果显示，人晶状体上皮细胞的体外存活能力有限，且细胞的增殖能力与供体年龄呈负相关。HH和H可有效抑制晶状体上皮细胞增殖。基于本报告结果，在白内障囊外摘除术中进行小而边缘光滑的连续环形撕囊可能会降低术后后囊混浊的发生率。
