Ning L, Yu J, Lin C
Department of Breast Cancer, Tianjin Cancer Hospital.
Zhonghua Zhong Liu Za Zhi. 1995 Mar;17(2):139-41.
During 1954-1977, among 2803 cases of breast cancer 99 (3.5%) had ipsilateral supraclavicular node mestastases. The results of treatment are reported, based on follow-up for more than 10 years. According to the treatment modality, the patients were divided into 4 groups: I. surgery with postoperative adjuvant chemotherapy and radiation therapy; II. radiation and chemotherapy; III. chemotherapy; IV. no treatment. In group I, surgical procedures consisted of segmental mastectomy in 6; simple mastectomy in 7; modified radical mastectomy in 16; standard radical mastectomy in 12, and extended radical mastectomy in 3. The over-all five-year survival rate was 9%. It was 18% (8/44) in group I, but only 5% (1/21) in group II. None survived for 5 years in group III and group IV. The results seem to indicate that more aggressive multi-modality treatment of breast cancer with ipsilateral supraclavicular lymph node metastases is indicated to expect better survival.
1954年至1977年间，在2803例乳腺癌患者中，99例（3.5%）出现同侧锁骨上淋巴结转移。本文报告了基于10年以上随访的治疗结果。根据治疗方式，患者被分为4组：I. 手术加术后辅助化疗和放疗；II. 放疗和化疗；III. 化疗；IV. 未治疗。在I组中，手术方式包括6例行乳房部分切除术；7例行单纯乳房切除术；16例行改良根治性乳房切除术；12例行标准根治性乳房切除术；3例行扩大根治性乳房切除术。总体五年生存率为9%。I组为18%（8/44），但II组仅为5%（1/21）。III组和IV组无患者存活5年。结果似乎表明，对于伴有同侧锁骨上淋巴结转移的乳腺癌，采用更积极的多模式治疗有望获得更好的生存率。
