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泰国中风幸存者中的痴呆症:212例患者分析

Dementia in Thai stroke survivors: analysis of 212 patients.

作者信息

Poungvarin N, Prayoonwiwat N, Devahastin V, Viriyavejakul A

机构信息

Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.

出版信息

J Med Assoc Thai. 1995 Jul;78(7):337-43.

PMID:7658177
Abstract

A cross-sectional designed study was done at Siriraj Hospital from 1990 to 1994 to determine the prevalence of dementia in Thai stroke survivors. Two hundred and twelve Thai stroke (both hemorrhage and infarction) survivors (132 males and 80 females) were enrolled in this study. The mean age of the study group was 62.78 (S.D. 11.12) years with the mean duration of stroke suffering of 2.09 (S.D. 2.74) years. All patients were screened for depression by using Thai Geriatric Depression Scale and patients with Alzheimer disease were excluded from the study. The Thai Mental State Examination (TMSE) is a standard test used in this study to identify stroke patients with dementia. Seventy stroke patients (33.02 per cent) scored below 23 points (cut-off point for dementia) and considered as dementia. Forty patients (18.88 per cent) scored below 20 points and were considered as having severe dementia, 30 patients (14.15 per cent) scored between 20-22 points (classified as mild to moderate dementia). Fifty-eight patients (27.36 per cent) were in the borderline group as they had TMSE scores between 23-25 points. Eighty four patients (39.62 per cent) of stroke survivors were determined as nondemented as their TMSE scores were over 25 points. The items of cognitive function tests in TMSE which were severely impaired in demented group were recall and calculation whereas registration and attention were relatively unaffected. Orientation and language were moderately impaired in the demented group.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

1990年至1994年在诗里拉吉医院开展了一项横断面设计研究,以确定泰国中风幸存者中痴呆症的患病率。本研究纳入了212名泰国中风(包括出血性和缺血性)幸存者(132名男性和80名女性)。研究组的平均年龄为62.78岁(标准差11.12),平均中风患病时长为2.09年(标准差2.74)。所有患者均使用泰国老年抑郁量表进行抑郁筛查,患有阿尔茨海默病的患者被排除在研究之外。泰国精神状态检查(TMSE)是本研究中用于识别患有痴呆症的中风患者的标准测试。70名中风患者(33.02%)得分低于23分(痴呆症临界值),被视为患有痴呆症。40名患者(18.88%)得分低于20分,被视为患有重度痴呆症,30名患者(14.15%)得分在20 - 22分之间(分类为轻度至中度痴呆症)。58名患者(27.36%)处于临界组,因为他们的TMSE得分在23 - 25分之间。84名中风幸存者(39.62%)被确定为未患痴呆症,因为他们的TMSE得分超过25分。在痴呆症组中,TMSE认知功能测试中严重受损的项目是回忆和计算,而登记和注意力相对未受影响。痴呆症组中的定向和语言功能受到中度损害。(摘要截选至250字)

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