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[玉米油给药对正常和营养不良的以牛奶喂养的婴儿血浆磷脂脂肪酸组成的影响]

[Effect of the administration of corn oil on the composition of fatty acids of plasma phospholipids in normal and malnourished infants fed with cow's milk].

作者信息

De Tomás M E, Mercuri O, De Serres C T, Marín M C, Rodrigo A

机构信息

Instituto de Investigaciones Bioquímicas de La Plata, Facultad de Ciencias Médicas, Universidad Nacional de La Plata.

出版信息

Medicina (B Aires). 1994;54(5 Pt 1):385-91.

PMID:7658971
Abstract

The effect of corn oil diet administration on the essential fatty acids (EFAs) profiles was evaluated in plasma phospholipids from normal and malnourished cow's milk fed infants nursing infants. A control group of only breast-fed was also selected for this study. The fatty acid composition was determined by gas-liquid chromatography and used as biochemical variable for evaluating EFA status. A fall in the proportion of fatty acids concomitant with an increase in the saturated fatty acids, consistent with a pattern of essential fatty acid deficiency (EFAD) was observed in the cow's milk fed infants, either normal or malnourished (Table 2). The corn oil administration was capable of restoring the fatty acid profile to normal values, similar to the values of the control group of breast-fed infants, even in malnourished infants, although during the 15 days test they did not correct their clinical syndrome of malnutrition (Table 3). Calculation of the product-precursor of the linoleic acid provided evidence for the positive effect of the corn oil administration.

摘要

在以正常和营养不良的母乳喂养婴儿为对象的研究中,评估了玉米油饮食摄入对血浆磷脂中必需脂肪酸(EFA)谱的影响。本研究还选取了仅以母乳喂养的对照组。通过气液色谱法测定脂肪酸组成,并将其用作评估EFA状态的生化变量。在以牛奶喂养的正常或营养不良婴儿中,观察到脂肪酸比例下降,同时饱和脂肪酸增加,这与必需脂肪酸缺乏(EFAD)模式一致(表2)。即使在营养不良的婴儿中,摄入玉米油也能够将脂肪酸谱恢复到正常值,类似于母乳喂养婴儿对照组的值,尽管在15天的测试期间他们并未纠正其临床营养不良综合征(表3)。亚油酸的产物-前体计算为摄入玉米油的积极作用提供了证据。

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