大鼠嗅上皮和犁鼻器中神经钙蛋白免疫反应性受体细胞。

Neurocalcin-immunoreactive receptor cells in the rat olfactory epithelium and vomeronasal organ.

作者信息

Iino S, Kobayashi S, Okazaki K, Hidaka H

机构信息

Department of Anatomy, Nagoya University School of Medicine, Japan.

出版信息

Neurosci Lett. 1995 May 19;191(1-2):91-4. doi: 10.1016/0304-3940(95)11568-2.

DOI:10.1016/0304-3940(95)11568-2

PMID:7659300

Abstract

Occurrence of neurocalcin, a calcium-binding protein with three EF hand motifs, was examined immunohistochemically in the rat olfactory epithelium and vomeronasal organ epithelium. Immunoreactivity was detected in receptor cells in these epithelia. Immunoreactions were distributed in cytoplasm associated with outer mitochondrial membrane, endoplasmic reticulum and microtubules. Olfactory and vomeronasal nerve fibers in the lamina propria exhibited immunoreactivity. Neurocalcin may participate in calcium signalling and cytoskeletal arrangement in receptor cells.

摘要

采用免疫组织化学方法检测了神经钙蛋白（一种具有三个EF手基序的钙结合蛋白）在大鼠嗅上皮和犁鼻器上皮中的表达情况。在这些上皮的受体细胞中检测到了免疫反应性。免疫反应分布于与线粒体外膜、内质网和微管相关的细胞质中。固有层中的嗅神经纤维和犁鼻神经纤维均表现出免疫反应性。神经钙蛋白可能参与受体细胞中的钙信号传导和细胞骨架排列。