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[肺炎链球菌败血症。40例病例分析]

[Streptococcus pneumoniae septicemia. Analysis of 40 cases].

作者信息

Noriega L M, González P, Canals C, Michaud P

机构信息

Servicio de Medicina, Hospital Dr Sótero del Rio, P Universidad Católica de Chile, Santiago.

出版信息

Rev Med Chil. 1994 Dec;122(12):1385-92.

PMID:7659913
Abstract

Sepsis due to Streptococcus pneumoniae has a high mortality. We report a retrospective review of 40 episodes of S pneumonia sepsis in adult patients during a two year period in a general hospital, that represented 11.3% of all sepsis observed in such hospital. Ninety two percent of infections were community acquired and in 95%, the portal of entry was the respiratory tract. Eighty five percent of patients had at least one risk factor such as alcohol abuse, unconsciousness or chronic pulmonary disease. Nine patients had suppurative complications (empyema in 4 cases, spontaneous bacterial peritonitis in 2, septic arthritis in 2 and meningitis in 1 case) and 12 (30%) died. The potential benefit of antipneumococcal vaccine as prevention should be considered in high risk subjects.

摘要

肺炎链球菌所致脓毒症死亡率很高。我们对一家综合医院两年内成年患者的40例肺炎链球菌脓毒症进行了回顾性研究,这些病例占该医院所有脓毒症病例的11.3%。92%的感染为社区获得性,95%的感染途径为呼吸道。85%的患者至少有一项危险因素,如酗酒、意识不清或慢性肺病。9例患者出现化脓性并发症(4例脓胸、2例自发性细菌性腹膜炎、2例脓毒性关节炎和1例脑膜炎),12例(30%)死亡。对于高危人群,应考虑使用抗肺炎球菌疫苗进行预防的潜在益处。

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