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原发性A组链球菌性腹膜炎

Primary group A streptococcal peritonitis.

作者信息

Graham J C, Moss P J, McKendrick M W

机构信息

Department of Infectious Diseases and Medicine, Royal Hallamshire Hospital, Sheffield, England.

出版信息

Scand J Infect Dis. 1995;27(2):171-2. doi: 10.3109/00365549509019001.

DOI:10.3109/00365549509019001
PMID:7660084
Abstract

Primary peritonitis caused by Group A beta-haemolytic streptococci (GAS) is extremely rare and is usually only seen in the presence of underlying disease. This report describes the case of a previously fit young woman who developed primary GAS peritonitis. She had a laparotomy performed at which large amounts of intra-peritoneal pus was identified but no focus of infection was found. Broad spectrum antibiotics were initially used, these were changed to intravenous benzylpenicillin when GAS was isolated. She made a good recovery and was discharged 2 weeks after admission on oral amoxycillin. The organism was serotyped as T3/M3/R3 (opacity factor negative) and it is interesting that the same serotype was isolated from a throat swab taken from her daughter. We also discuss the possible routes of infection and the epidemiology of invasive GAS disease.

摘要

A组β溶血性链球菌(GAS)引起的原发性腹膜炎极为罕见,通常仅在存在基础疾病的情况下出现。本报告描述了一名既往健康的年轻女性发生原发性GAS腹膜炎的病例。她接受了剖腹手术,术中发现大量腹腔脓液,但未发现感染源。最初使用了广谱抗生素,分离出GAS后改为静脉注射苄青霉素。她恢复良好,入院2周后口服阿莫西林出院。该菌株血清型为T3/M3/R3(透明质酸酶阴性),有趣的是,从她女儿的咽拭子中分离出了相同的血清型。我们还讨论了可能的感染途径和侵袭性GAS疾病的流行病学。

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