Gillum R F
Centers for Disease Control and Prevention, National Center for Health Statistics, Hyattsville, MD 20782, USA.
Stroke. 1995 Sep;26(9):1724-8. doi: 10.1161/01.str.26.9.1724.
Results of North American and European trials of carotid endarterectomy published in 1991 may have affected the frequency of the procedure in the United States. Therefore, data from a national survey of hospital discharges were examined to determine whether rates of carotid endarterectomy and arteriography increased after 1991 and whether race and sex variations in rates have persisted.
Data from the National Hospital Discharge Survey were examined for the years 1980 through 1993. Estimated numbers of procedures performed in nonfederal US hospitals were used to compute rates per 100,000 population by year, age, race, and sex.
In persons aged 65 years and over, the rate of carotid endarterectomy increased rapidly between 1980 and 1983 with a slight further increase through 1985. A marked fall in the rate occurred between 1985 and 1988, followed by a plateau and a sharp upturn in 1992. After 1985, there was a steady decline in the rate of cerebral arteriography procedures in hospital. No reliable data were available on outpatient cerebral arteriography. Throughout the period, whites had estimated rates of carotid endarterectomy procedures over four times higher than blacks. Whites also had higher rates of cerebral arteriography, but the disparity was not as great as for endarterectomy. Rates of carotid endarterectomy were 60% higher in men than women, but rates of cerebral arteriography were only 9% higher in men than women.
Rates of carotid endarterectomy increased sharply after the 1991 publication of trial results. Marked racial disparities in the use of this procedure persist and require further evaluation.
1991年发表的北美和欧洲颈动脉内膜切除术试验结果可能影响了该手术在美国的实施频率。因此,对一项全国性医院出院调查的数据进行了分析,以确定1991年后颈动脉内膜切除术和动脉造影术的发生率是否增加,以及发生率在种族和性别上的差异是否持续存在。
对1980年至1993年期间美国国家医院出院调查的数据进行分析。利用美国非联邦医院实施手术的估计数量,按年份、年龄、种族和性别计算每10万人的手术发生率。
在65岁及以上人群中,颈动脉内膜切除术的发生率在1980年至1983年之间迅速上升,并在1985年略有进一步上升。1985年至1988年发生率显著下降,随后趋于平稳,并在1992年急剧上升。1985年以后,医院中脑动脉造影术的发生率稳步下降。门诊脑动脉造影术没有可靠的数据。在整个研究期间,白人颈动脉内膜切除术的估计发生率比黑人高出四倍多。白人的脑动脉造影术发生率也较高,但差距没有颈动脉内膜切除术那么大。男性颈动脉内膜切除术的发生率比女性高60%,但男性脑动脉造影术的发生率仅比女性高9%。
1991年试验结果发表后,颈动脉内膜切除术的发生率急剧上升。该手术在使用上存在明显的种族差异,需要进一步评估。