O'Callaghan C J, Phillips P A, Krum H, Howes L G
Clinical Pharmacology & Therapeutics Unit, University of Melbourne, Austin Hospital, Heidelberg, Australia.
Am J Hypertens. 1995 Jun;8(6):572-7. doi: 10.1016/0895-7061(95)00041-M.
Office blood pressure (OBP), ambulatory blood pressure (ABP), and vascular reactivity were measured in 12 normotensive 'social' drinkers (mean alcohol consumption of 9.7 +/- 3.1 g/day) after 4 days of alcohol consumption (1 g/kg/day) and compared with the effects of an isocaloric substitute (sucrose, 1.75 g/kg/day) or no intervention. Alcohol consumption did not affect OBP or 24-mean ABP but appeared to decrease nocturnal systolic and diastolic blood pressure soon after consumption. Although vascular reactivity did not differ between the groups, the blood pressure rise in response to isometric exercise tended to be lower following alcohol. Thus, short-term alcohol ingestion by normotensive 'social' drinkers does not increase office or ambulatory blood pressure.
对12名血压正常的“社交型”饮酒者(平均酒精摄入量为9.7±3.1克/天)在饮酒4天(1克/千克/天)后测量其诊室血压(OBP)、动态血压(ABP)和血管反应性,并与等热量替代物(蔗糖,1.75克/千克/天)或不干预的效果进行比较。饮酒并未影响诊室血压或24小时平均动态血压,但在饮酒后不久似乎会降低夜间收缩压和舒张压。尽管各组之间的血管反应性没有差异,但饮酒后等长运动引起的血压升高往往较低。因此,血压正常的“社交型”饮酒者短期饮酒不会增加诊室血压或动态血压。