Myers M G, Oh P I, Reeves R A, Joyner C D
Division of Cardiology, Sunnybrook Health Science Centre, Toronto, Ontario, Canada.
Am J Hypertens. 1995 Jun;8(6):591-7. doi: 10.1016/0895-7061(95)00049-U.
Patients receiving drug therapy for hypertension in the tertiary care setting frequently exhibit higher office readings compared to ambulatory blood pressure values (white coat effect). In this study, the prevalence of a white coat effect was determined in an unselected population of 147 hypertensive patients receiving treatment from their family physicians in the community. The proportion of patients with a white coat effect (defined as office - ambulatory blood pressure > or = 20/10 mm Hg) was significantly (P < .001) higher when based upon the family physician's routine blood pressure readings (91/147), compared to special readings taken by the family physician for the study (54/147) or readings taken by a research nurse (30/147). There was a higher correlation (P < .05) between the ambulatory systolic blood pressure and the nurse's readings (r = 0.62) or special physician's readings (r = 0.55) v the routine physician's readings (r = 0.34). Left ventricular mass index as measured by echocardiography correlated (P < .01) with the special physician (r = 0.27), nurse (r = 0.23), and ambulatory systolic blood pressure readings (r = 0.24), but not with the routine physician's readings (r = 0.06). A white coat effect is frequently present in treated hypertensive patients when blood pressure is recorded by family physicians in routine clinical practice.
在三级医疗环境中接受高血压药物治疗的患者,与动态血压值相比,其诊室血压读数通常更高(白大衣效应)。在本研究中,在一个未经过挑选的、由社区家庭医生治疗的147名高血压患者群体中确定白大衣效应的患病率。当基于家庭医生的常规血压读数时(91/147),白大衣效应患者的比例(定义为诊室血压 - 动态血压≥20/10 mmHg)显著更高(P <.001),相比之下,家庭医生为该研究进行的特殊读数时(54/147)或研究护士进行的读数时(30/147)。动态收缩压与护士的读数(r = 0.62)或医生的特殊读数(r = 0.55)之间的相关性高于与常规医生读数(r = 0.34)(P <.05)。通过超声心动图测量的左心室质量指数与医生的特殊读数(r = 0.27)、护士的读数(r = 0.23)和动态收缩压读数(r = 0.24)相关(P <.01),但与常规医生的读数(r = 0.06)不相关。当家庭医生在常规临床实践中记录血压时,接受治疗的高血压患者中经常存在白大衣效应。