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大鼠小脑前下动脉选择性闭塞后脑干缺血的听觉脑干反应结果

Auditory brainstem response findings in brainstem ischemia following selective occlusion of the anterior inferior cerebellar artery in the rat.

作者信息

Inui H, Murai T, Matsunaga T

机构信息

Department of Otorhinolaryngology, Nara Medical College, Japan.

出版信息

Eur Arch Otorhinolaryngol. 1995;252(3):181-5. doi: 10.1007/BF00178109.

DOI:10.1007/BF00178109
PMID:7662355
Abstract

Auditory brainstem responses (ABRs) were measured ipsilaterally (n = 13) or contralaterally (n = 5) after inducing permanent right and left anterior inferior cerebellar artery (AICA) occlusion. Three types of wave patterns were classified when ABRs were recorded ipsilaterally. In type 1 (n = 4) all components disappeared; in type 2 (n = 2) all components disappeared transiently and then reappeared; and in type 3 (n = 7) only the latency difference between components I and IV increased. These findings indicate that all components reappeared in type 2 responses because cochlear blood flow was re-established quickly by collateral circulation, while type 3 changes reflected the relative sensitivity of the cochlea to ischemic damage when compared with the rest of the auditory pathways. When the ABRs were recorded contralaterally, characteristic findings included a delay in latency of component IV and a significant increase in inter-peak latency in components I-IV and IIb-IV.

摘要

在造成永久性右侧和左侧小脑前下动脉(AICA)闭塞后,分别从同侧(n = 13)或对侧(n = 5)测量听觉脑干反应(ABR)。在同侧记录ABR时,可将波形分为三种类型。在1型(n = 4)中,所有成分均消失;在2型(n = 2)中,所有成分短暂消失后又重新出现;在3型(n = 7)中,仅I波和IV波之间的潜伏期差异增加。这些发现表明,2型反应中所有成分重新出现是因为侧支循环迅速重建了耳蜗血流,而3型变化反映了与听觉通路其他部分相比,耳蜗对缺血性损伤的相对敏感性。当从对侧记录ABR时,特征性表现包括IV波潜伏期延迟以及I-IV波和IIb-IV波的峰间潜伏期显著增加。

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引用本文的文献

1
Brainstem ischemic damage following occlusion of the blood vessels in the rat's posterior cerebral circulation.大鼠大脑后循环血管闭塞后引起的脑干缺血性损伤。
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本文引用的文献

1
Laser-Doppler measurements and electrocochleography during ischemia of the guinea pig cochlea: implications for hearing preservation in acoustic neuroma surgery.豚鼠耳蜗缺血期间的激光多普勒测量和电耳蜗图:对听神经瘤手术中听力保护的意义。
Ann Otol Rhinol Laryngol. 1993 Feb;102(2):127-36. doi: 10.1177/000348949310200210.
2
Effects of hyperthermia on the auditory-evoked brainstem responses in mice.高温对小鼠听觉诱发脑干反应的影响。
Audiology. 1993 Nov-Dec;32(6):344-55. doi: 10.3109/00206099309071865.
3
Maturation of auditory evoked potentials in young guinea pigs with binaural conductive hearing loss.
双侧传导性听力损失幼龄豚鼠听觉诱发电位的成熟情况
Eur Arch Otorhinolaryngol. 1993;250(6):362-5. doi: 10.1007/BF00188388.
4
Autoradiographic measurement of regional brainstem blood flow: occlusion of the anterior inferior cerebellar artery.
Eur Arch Otorhinolaryngol. 1994;251(4):233-7. doi: 10.1007/BF00628430.
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Autoradiographic measurement of regional brainstem blood flow. Findings after 2 hours of occlusion of the unilateral anterior inferior cerebellar artery and 30 minutes' occlusion of the unilateral vertebral artery.脑干局部血流的放射自显影测量。单侧小脑前下动脉闭塞2小时和单侧椎动脉闭塞30分钟后的结果。
Acta Otolaryngol Suppl. 1995;519:143-8. doi: 10.3109/00016489509121890.
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Auditory brain stem responses in the cat. II. Effects of lesions.猫的听觉脑干反应。II. 损伤的影响。
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Auditory brain stem responses in the cat. I. Intracranial and extracranial recordings.猫的听觉脑干反应。I. 颅内和颅外记录。
Electroencephalogr Clin Neurophysiol. 1980 Feb;48(2):154-73. doi: 10.1016/0013-4694(80)90301-6.