Noureddine S N
School of Nursing, University of California at Los Angeles, USA.
Am J Crit Care. 1995 Jul;4(4):272-7; quiz 278-9.
Successful management of patients after coronary angioplasty requires careful monitoring of the coagulation status in order to titrate heparin therapy and prevent thrombosis or bleeding. Traditionally, the activated partial thromboplastin time was used to monitor heparin therapy. Recently, however, use of activated clotting time is gaining more support because it can be performed at the bedside and is cost-effective. This article reviews the research on the use of activated clotting time in titrating heparin therapy in angioplasty patients. Although the literature supports the use of activated clotting time in angioplasty, limitations of the studies and the different methodologies used preclude generalization of results. More research is needed to confirm the efficiency and effectiveness of the activated clotting time in monitoring heparin therapy.
冠状动脉血管成形术后患者的成功管理需要仔细监测凝血状态，以便调整肝素治疗并预防血栓形成或出血。传统上，活化部分凝血活酶时间用于监测肝素治疗。然而，最近活化凝血时间的应用获得了更多支持，因为它可以在床边进行且具有成本效益。本文综述了关于在血管成形术患者中使用活化凝血时间调整肝素治疗的研究。尽管文献支持在血管成形术中使用活化凝血时间，但研究的局限性和所采用的不同方法妨碍了结果的推广。需要更多研究来证实活化凝血时间在监测肝素治疗中的有效性和效能。
