Jain R K, Liu X G, Oruganti S R, Chandrasekaran E V, Matta K L
Department of Gynecologic Oncology, Roswell Park Cancer Institute, Buffalo, NY 14263, USA.
Carbohydr Res. 1995 Jul 11;271(2):185-96. doi: 10.1016/0008-6215(95)00073-3.
The stereoselective syntheses of one pentasaccharide and one tetrasaccharide containing the Glc-alpha-(1-->3)-Man-alpha moiety as their terminal unit, as well as one tetrasaccharide and one trisaccharide containing the Man-alpha-(1-->2)-Man-alpha terminal unit were accomplished through the utilization of two key glycosyl donors, namely, 4-pentenyl 3-O-acetyl-2,4,6-tri-O-benzyl-alpha-D-mannopyranoside and ethyl 2-O-acetyl-3,4,6-tri-O-benzyl-1-thio-alpha-D-mannopyranoside.
通过使用两种关键的糖基供体，即4-戊烯基3-O-乙酰基-2,4,6-三-O-苄基-α-D-甘露吡喃糖苷和乙基2-O-乙酰基-3,4,6-三-O-苄基-1-硫代-α-D-甘露吡喃糖苷，完成了一种以Glc-α-(1→3)-Man-α部分作为末端单元的五糖和一种四糖，以及一种以Man-α-(1→2)-Man-α末端单元的四糖和一种三糖的立体选择性合成。
