Yamaguchi K, Komori T, Kanda T, Hirose K, Tanabe H
Department of Neurology, Tokyo Metropolitan Neurological Hospital, Japan.
Rinsho Shinkeigaku. 1995 May;35(5):500-4.
We reported a case of myokymia with abnormal F response. A 60-year-old male with chronic alcoholism was admitted to our hospital with complaint of muscle cramp in both legs just after drinking. Neurological examination revealed muscle pain and weakness of the legs, absence of bilateral Achilles tendon reflexes and prominent myokymia in his right quadriceps femoris and left calf muscles. The electrophysiological examination showed reduced conduction velocity, high amplitude, increased number of phases and long duration of F responses suggesting increased excitability of motoneuron pool. The epidural nerve block brought about a disappearance of the myokymia and an improvement of the abnormal features of F response. The myokymia gradually tended to be milder in the clinical course. The relationship between the myokymia and the abnormal F responses indicated that the increased excitability of spinal motoneurons might play an important role on the generation of myokymia of this patient.
我们报告了一例伴有异常F波的肌束震颤病例。一名60岁慢性酒精中毒男性因饮酒后双下肢肌肉痉挛而入院。神经系统检查发现双下肢肌肉疼痛、无力，双侧跟腱反射消失，右股四头肌和左小腿肌肉有明显的肌束震颤。电生理检查显示传导速度减慢、波幅增高、F波时限增宽及多相波增多，提示运动神经元池兴奋性增加。硬膜外神经阻滞使肌束震颤消失，F波异常特征改善。在临床过程中，肌束震颤逐渐趋于减轻。肌束震颤与异常F波之间的关系表明，脊髓运动神经元兴奋性增加可能在该患者肌束震颤的发生中起重要作用。
