De Meuter F, De Decker H
Zentralbl Bakteriol Orig A. 1975 Nov;233(3):421-30.
The indirect fluorescent antibody (IFA) test effected with anti-human conjugate gives appreciably equivalent results to those obtained with the dye (SABIN-FELDMAN) test, but weak serum dilutions may raise non specific reactions, due to the presence of substances possessing the IgM antibody properties. Those substances are not present in the serum of children during the first months of their life. The application of an anti-IgG conjugate allows to prevent those unspecific reactions. The application of the modified IFA test for detecting the toxoplasmic infection during pregnancy and the use of the REMINGTON test for the early diagnosis of the congenital toxoplasmosis are discussed.
用抗人结合物进行的间接荧光抗体（IFA）试验所得结果与用染料（SABIN - FELDMAN）试验得到的结果相当，但由于存在具有IgM抗体特性的物质，血清稀释度较低时可能会引发非特异性反应。在婴儿出生后的头几个月，其血清中不存在这些物质。应用抗IgG结合物可避免这些非特异性反应。本文讨论了改良IFA试验在孕期检测弓形虫感染中的应用以及REMINGTON试验在先天性弓形虫病早期诊断中的应用。
