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嗅觉受体样基因位于人类主要组织相容性复合体中。

Olfactory receptor-like genes are located in the human major histocompatibility complex.

作者信息

Fan W, Liu Y C, Parimoo S, Weissman S M

机构信息

Boyer Center for Molecular Medicine, Yale University School of Medicine, New Haven, Connecticut 06510, USA.

出版信息

Genomics. 1995 May 1;27(1):119-23. doi: 10.1006/geno.1995.1013.

DOI:10.1006/geno.1995.1013
PMID:7665158
Abstract

The murine major histocompatibility complex (MHC) includes sequences that are responsible for haplotype-specific odor types that, in turn, influence mating preference. We report that there are several olfactory receptor genes or pseudogenes in the Class I region of the human MHC. At least one of these genes is intact, appears to encode an mRNA, and is quite homologous to a previously reported murine olfactory receptor.

摘要

小鼠主要组织相容性复合体(MHC)包含一些序列,这些序列决定了单倍型特异性气味类型,进而影响交配偏好。我们报告称,在人类MHC的I类区域存在几个嗅觉受体基因或假基因。这些基因中至少有一个是完整的,似乎能编码一种mRNA,并且与先前报道的小鼠嗅觉受体高度同源。

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