Wolf G
Department of Nutritional Sciences, University of California, Berkeley 94720, USA.
Nutr Rev. 1995 May;53(5):134-7. doi: 10.1111/j.1753-4887.1995.tb01537.x.
The enzyme beta-carotene-15,15'-dioxygenase from guinea pig intestinal mucosa was found to cleave beta-carotene and produce 2 mol of retinal for 1 mol of beta-carotene. However, extensive evidence exists also for random (excentric) cleavage, resulting in retinoic acid and retinal, with a preponderance of apocarotenals formed as intermediates.
已发现豚鼠肠黏膜中的β-胡萝卜素-15,15'-双加氧酶可裂解β-胡萝卜素,每1摩尔β-胡萝卜素产生2摩尔视黄醛。然而,也有大量证据表明存在随机(偏心)裂解,生成视黄酸和视黄醛,其中大量的阿朴胡萝卜醛作为中间体形成。