[Role of monokines in the development of the immune response during physical exertion and administration of essentiale].

Exercises and essential administration lead to the emergence of differently dense red blood cells that have opposite immunomodulating properties. Such red blood cells induce or stimulate the release of immunomodulating factors by various splenic macrophageal populations. Cell interaction largely determine the magnitude of the body's responses to T-dependent antigens during strenuous exercise and essential administration.