Ryden S E, Silverman E M
Arch Pathol Lab Med. 1976 Feb;100(2):87-90.
The histologic lesions produced in the brain by stereotactic chemosurgery and cryosurgery are reviewed in four patients who died from 25 days to 15 years postoperatively. Three of four patients had damage to the internal capsule and died of pulmonary emboli. The early lesions are histologically nonspecific, but the old lesions of chemopallidectomy and chemothalamectomy in one patient contained metaplastic bone. Lesions produced by freezing are more discrete than those made by chemical means.
对4例术后25天至15年死亡患者的脑部立体定向化学手术和冷冻手术所产生的组织学损伤进行了回顾。4例患者中有3例内囊受损，死于肺栓塞。早期损伤在组织学上无特异性，但1例患者化学性苍白球切除术和化学性丘脑切除术后的陈旧性损伤包含化生骨。冷冻产生的损伤比化学方法造成的损伤更局限。
