Aspöck C, Bettelheim D, Fischl F, Hirschl A M, Makristathis A, Prückl P, Willinger B, Rotter M L
Hygiene-Institut, Universität Wien.
Wien Klin Wochenschr. 1995;107(14):423-6.
In order to investigate a presumed association of certain anamnestic data with Chlamydia trachomatis infection of infertile women, appropriate specimens were examined from 100 patients of an infertility clinic. PCR and nucleic acid hybridization were positive in 5% of the patients, corresponding in both tests; IgG was found in 31% and IgA in 5% of patients. The prevalence was highest in the age-group of 26-35 years (21 of 55) and higher in patients who had been trying to conceive for > 2 years (12 of 37) as than those trying < or = 2 years (3 of 13). The proportion of IgG-positive women was significantly (p = 0.03) smaller in Turkish patients (3 of 22) than in those of other origin (11 of 33 from former Yugoslavia and 15 of 39 Austrian women). The prevalence was higher in patients with reported pelvic inflammatory disease (11 of 30) as compared to patients without (15 of 50). With a pathological state of the Fallopian tubes the prevalence was 12 of 25, with normal tubes 6 of 18 (p > 0.05). Thus, there seem to exist anamnestic hints as to chlamydial infections. Because of their high prevalence in patients with sterility we recommend screening for chlamydial infection prior to undertaking any invasive diagnostic procedure of the Fallopian tubes.
为了研究某些既往病史数据与不育女性沙眼衣原体感染之间的假定关联，我们对一家不育诊所的100名患者进行了适当标本的检查。PCR和核酸杂交在5%的患者中呈阳性，两种检测结果一致；31%的患者检测到IgG，5%的患者检测到IgA。患病率在26 - 35岁年龄组最高（55人中21人），在尝试受孕超过2年的患者中更高（37人中12人），高于尝试受孕≤2年的患者（13人中3人）。土耳其患者中IgG阳性女性的比例（22人中3人）显著低于其他来源的患者（前南斯拉夫的33人中11人，奥地利女性的39人中15人）（p = 0.03）。报告有盆腔炎病史患者的患病率（30人中11人）高于无盆腔炎病史患者（50人中15人）。输卵管病理状态异常的患者患病率为25人中12人，输卵管正常的患者患病率为18人中6人（p > 0.05）。因此，似乎存在衣原体感染的既往病史线索。鉴于衣原体感染在不育患者中患病率较高，我们建议在对输卵管进行任何侵入性诊断程序之前进行衣原体感染筛查。
