Hudson B J, van der Meijden W I, Lupiwa T, Howard P, Tabua T, Tapsall J W, Phillips E A, Lennox V A, Backhouse J L, Pyakalyia T
Royal North Shore Hospital, Prince of Wales Hospital, Sydney, Australia.
P N G Med J. 1994 Sep;37(3):152-60.
The first multicentre survey of sexually transmitted diseases (STDs) performed in Papua New Guinea was conducted in STD clinics in five towns, Port Moresby, Goroka, Rabaul, Lae and Daru, from September 1989 to May 1990. Infections with Neisseria gonorrhoeae and Chlamydia trachomatis (alone or in combination) were common. Penicillinase-producing N. gonorrhoeae (PPNG) represented 44% of all gonococcal isolates but significant intrinsic resistance to penicillin was not found. Of the other antibiotics tested, significant elevation of minimum inhibitory concentration (MIC) was common only for tetracycline, although no high-level tetracycline resistance was detected. C. trachomatis was detected by direct immunofluorescence (DIF) in 26% of 210 males and 27% of 64 females. 10% (21/210) of males and 11% (7/64) of females were both DIF positive for C. trachomatis and culture positive for N. gonorrhoeae. Of 203 males and 78 females tested, 5% and 12%, respectively, had serological evidence of current syphilis infection. Clinically, genital ulcer disease was most commonly due to syphilis, donovanosis or genital herpes, while specific vaginal infections were commonly seen in female patients attending Port Moresby and Lae STD clinics.
1989年9月至1990年5月，在巴布亚新几内亚的莫尔斯比港、戈罗卡、拉包尔、莱城和达鲁这五个城镇的性病诊所开展了该国首次关于性传播疾病（STD）的多中心调查。淋病奈瑟菌和沙眼衣原体感染（单独感染或合并感染）较为常见。产青霉素酶淋病奈瑟菌（PPNG）占所有淋病奈瑟菌分离株的44%，但未发现对青霉素有显著的固有耐药性。在测试的其他抗生素中，仅四环素的最低抑菌浓度（MIC）显著升高较为常见，不过未检测到高水平的四环素耐药性。通过直接免疫荧光法（DIF）在210名男性中的26%以及64名女性中的27%检测到沙眼衣原体。10%（21/210）的男性和11%（7/64）的女性沙眼衣原体DIF检测呈阳性且淋病奈瑟菌培养呈阳性。在接受检测的203名男性和78名女性中，分别有5%和12%有当前梅毒感染的血清学证据。临床上，生殖器溃疡疾病最常见的病因是梅毒、杜诺凡病或生殖器疱疹，而在莫尔斯比港和莱城性病诊所就诊的女性患者中常见特定的阴道感染。
