Williams N, Doyle A, Brighouse D
Shackleton Department of Anaesthesia, Southampton General Hospital.
Br J Anaesth. 1995 Jul;75(1):9-11. doi: 10.1093/bja/75.1.9.
We have compared 2% lignocaine 3.5 ml with 0.5% hyperbaric bupivacaine 3 ml in a randomized, double-blind study in 30 patients undergoing subarachnoid anaesthesia for transurethral surgery. A sensory level of T10 was produced more quickly (P = 0.0001) and maximum height reached sooner (P = 0.0002) with lignocaine, although there was a greater reduction in systolic arterial pressure (P = 0.03) and a trend towards slower heart rates (P = 0.056). Return of full sensory and motor function occurred earlier with lignocaine (P = 0.00005 and P = 0.02).
我们在一项随机双盲研究中，对30例接受蛛网膜下腔麻醉以进行经尿道手术的患者，比较了2% 3.5毫升的利多卡因与0.5% 3毫升的高压布比卡因。利多卡因产生T10感觉平面的速度更快（P = 0.0001），达到的最大高度更早（P = 0.0002），尽管收缩压下降幅度更大（P = 0.03），且心率有减慢趋势（P = 0.056）。利多卡因使感觉和运动功能完全恢复的时间更早（P = 0.00005和P = 0.02）。
