Zhang Y Q, Tang J S, Yuan B, Jia H
Research Laboratory of Neurophysiology, Xian Medical University, Shaanxi, People's Republic of China.
Neuroreport. 1995 Jun 19;6(9):1237-40. doi: 10.1097/00001756-199506090-00002.
Bilateral electrolytic lesions of the thalamic nucleus submedius (Sm) facilitated the TF reflex and attenuated the antinociception evoked by hindlimb electrical stimulation with high intensities in lightly anaesthetized rats. However, the antinociception produced by low intensity hindlimb stimulation was unchanged, except that the after-effect was reduced. The results show that the Sm is probably involved in pain modulation and plays an important role in mediation of the antinociception elicited by high intensity peripheral stimulation.
