Insulin expression: is VNTR allele 698 really anomalous? - Suppr | 超能文献

Insulin expression: is VNTR allele 698 really anomalous?

作者信息

McGinnis R E, Spielman R S

出版信息

Nat Genet. 1995 Aug;10(4):378-80. doi: 10.1038/ng0895-378.

DOI:10.1038/ng0895-378

Abstract

摘要

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Insulin expression: is VNTR allele 698 really anomalous?

Nat Genet. 1995 Aug;10(4):378-80. doi: 10.1038/ng0895-378.

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Imprinted and genotype-specific expression of genes at the IDDM2 locus in pancreas and leucocytes.IDDM2基因座上的基因在胰腺和白细胞中的印记及基因型特异性表达。

J Autoimmun. 1996 Jun;9(3):397-403. doi: 10.1006/jaut.1996.0054.

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Insulin expression in human thymus is modulated by INS VNTR alleles at the IDDM2 locus.人胸腺中的胰岛素表达受IDDM2位点的胰岛素可变数目串联重复序列（INS VNTR）等位基因调控。

Nat Genet. 1997 Mar;15(3):289-92. doi: 10.1038/ng0397-289.

4

The insulin gene is transcribed in the human thymus and transcription levels correlated with allelic variation at the INS VNTR-IDDM2 susceptibility locus for type 1 diabetes.胰岛素基因在人类胸腺中被转录，且转录水平与1型糖尿病的胰岛素可变数目串联重复序列- IDDM2易感位点的等位基因变异相关。

Nat Genet. 1997 Mar;15(3):293-7. doi: 10.1038/ng0397-293.

5

Susceptibility to human type 1 diabetes at IDDM2 is determined by tandem repeat variation at the insulin gene minisatellite locus.IDDM2位点对人类1型糖尿病的易感性由胰岛素基因小卫星位点的串联重复变异决定。

Nat Genet. 1995 Mar;9(3):284-92. doi: 10.1038/ng0395-284.

6

The variable number of tandem repeats upstream of the insulin gene is a susceptibility locus for latent autoimmune diabetes in adults.胰岛素基因上游可变串联重复序列是成人隐匿性自身免疫性糖尿病的一个易感位点。

Diabetes. 2006 Jun;55(6):1890-4. doi: 10.2337/db06-0089.

7

Insulin VNTR allele-specific effect in type 1 diabetes depends on identity of untransmitted paternal allele. The IMDIAB Group.1型糖尿病中胰岛素可变数目串联重复序列（VNTR）的等位基因特异性效应取决于未传递的父本等位基因的身份。IMDIAB研究小组。

Nat Genet. 1997 Nov;17(3):350-2. doi: 10.1038/ng1197-350.

8

Heterogeneity of class I INS VNTR allele association with insulin secretion in obese children.肥胖儿童中I类胰岛素基因可变数目串联重复序列（INS VNTR）等位基因与胰岛素分泌的异质性。

Physiol Genomics. 2006 May 16;25(3):480-4. doi: 10.1152/physiolgenomics.00311.2005. Epub 2006 Mar 28.

9

Strong association of insulin gene INS-VNTR polymorphisms with type 1 diabetes in the Romanian population.胰岛素基因INS-VNTR多态性与罗马尼亚人群1型糖尿病的强关联。

Rom J Intern Med. 2004;42(2):313-23.

10

IDDM2-VNTR-encoded susceptibility to type 1 diabetes: dominant protection and parental transmission of alleles of the insulin gene-linked minisatellite locus.IDDM2可变数目串联重复序列编码的1型糖尿病易感性：胰岛素基因连锁微卫星位点等位基因的显性保护及亲代传递

J Autoimmun. 1996 Jun;9(3):415-21. doi: 10.1006/jaut.1996.0057.

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Association of tyrosine hydroxylase 01 (TH01) microsatellite and insulin gene (INS) variable number of tandem repeat (VNTR) with type 2 diabetes and fasting insulin secretion in Mexican population.酪氨酸羟化酶 01（TH01）微卫星和胰岛素基因（INS）可变串联重复（VNTR）与墨西哥人群 2 型糖尿病及空腹胰岛素分泌的关联。

J Endocrinol Invest. 2024 Mar;47(3):571-583. doi: 10.1007/s40618-023-02175-4. Epub 2023 Aug 25.

2

Diabetes susceptibility at IDDM2 cannot be positively mapped to the VNTR locus of the insulin gene.胰岛素依赖型糖尿病2型（IDDM2）的糖尿病易感性不能正向定位到胰岛素基因的可变数目串联重复序列（VNTR）位点。

Diabetologia. 1996 May;39(5):594-9. doi: 10.1007/BF00403307.