Helliwell P S, O'Hara M
Royal Infirmary, Huddersfield.
Br J Rheumatol. 1995 Jul;34(7):673-6. doi: 10.1093/rheumatology/34.7.673.
To assess the correspondence between ideal and actual monitoring for disease-modifying anti-rheumatic drugs and the reasons for protocol failure, and the sharing of this task between primary and secondary care, we studied 249 patients with rheumatoid arthritis in a single district general hospital. Ideal monitoring protocols were derived from data sheets and from the rheumatological literature. Overall the ideal protocol was followed in 65% of cases: this ranged from 93% for methotrexate to 26% for sodium aurothiromalate. Most of the monitoring was done in general practice (e.g. 67% of all blood tests) and, with some exceptions, general practitioners (GPs) were willing to perform this task. However, many GPs reported logistic differences with specimen transfer and expressed the need for more information and support. Poor communication between hospital, patient and GP was also found to be a cause of protocol failure.
为评估改善病情抗风湿药物理想监测与实际监测之间的符合情况、方案未执行的原因,以及基层医疗与二级医疗之间该任务的分担情况,我们在一家地区综合医院对249例类风湿关节炎患者进行了研究。理想监测方案源自药品说明书和风湿病学文献。总体而言,65%的病例遵循了理想方案:甲氨蝶呤为93%,金硫葡糖为26%。大多数监测在全科医疗中进行(如所有血液检查的67%),且在某些例外情况下,全科医生(GP)愿意承担此项任务。然而,许多全科医生报告了标本转运方面的后勤差异,并表示需要更多信息和支持。医院、患者和全科医生之间沟通不畅也是方案未执行的一个原因。