Martikaĭnen Z M
Klin Lab Diagn. 1995 Jul-Aug(4):45-8.
The role of microorganisms belonging to the genus Corynebacterium in normalization of vaginal biocenosis by creating acid medium is discussed. A total of 300 samples of lochia and vaginal and cervical secretion were examined, 140 of these taken from women without gynecological diseases and women with a normal course of the postpartum period (controls) and 160 from patients with colpitis of various origins and a complicated course of the puerperium. An appreciable increase of the level of diphtheroids was observed in the lochia of control subjects and in all samples of patients (p < 0.01). Eight species of Corynebacterium were isolated. Urease-negative C. minutissimum, C. equi, C. aquaticum, and C. xerosis predominated in both controls and patients (p < 0.01). Opportunistic C. bovis, C. enzymicum, C. kutshevi, and C. sp. possessing urease activity were seldom isolated. No differences between the 2 groups in the species composition of the isolated bacteria were detected (p > 0.05). Two species of Corynebacterium were sometimes isolated from the same sample, this being more frequently with vaginal and cervical secretion samples than with lochia both in controls and patients (p < 0.01). The most incident association was C. aquaticum and C. equi. 59.6 +/- 2.7 isolated strains proved to be sensitive to antibiotics manufactured in this country.
本文讨论了棒状杆菌属微生物通过创造酸性环境在阴道生物群落正常化中的作用。共检查了300份恶露、阴道及宫颈分泌物样本，其中140份取自无妇科疾病且产后恢复正常的女性（对照组），160份取自各种原因引起的阴道炎及产褥期复杂病程的患者。在对照组的恶露及所有患者样本中，均观察到类白喉杆菌水平显著升高（p<0.01）。分离出8种棒状杆菌。在对照组和患者中，脲酶阴性的极小棒状杆菌、马棒状杆菌、水生棒状杆菌和干燥棒状杆菌占主导地位（p<0.01）。具有脲酶活性的机会致病菌牛棒状杆菌、产酶棒状杆菌、库氏棒状杆菌和棒状杆菌属很少分离到。两组分离细菌的种类组成无差异（p>0.05）。有时会从同一样本中分离出两种棒状杆菌，在对照组和患者中，这种情况在阴道及宫颈分泌物样本中比在恶露中更常见（p<0.01）。最常见的组合是水生棒状杆菌和马棒状杆菌。59.6±2.7株分离菌株对该国生产的抗生素敏感。
