Huilgol S C, Liddell K, Black M M
St John's Institute of Dermatology, St Thomas' Hospital, London, UK.
Clin Exp Dermatol. 1995 Jan;20(1):51-3. doi: 10.1111/j.1365-2230.1995.tb01283.x.
Generalized granuloma annulare (GA) is a chronic and widespread form of GA, less common than the localized type, in which the primary papular lesions may be arranged in either predominantly annular or non-annular configurations. Associations with numerous systemic disorders, including malignancies of the haematopoietic system, have been reported. There is a marked tendency to show the isomorphic or Koebner phenomenon. We report a most unusual case of generalized non-annular GA associated with chronic myelomonocytic leukaemia and myelodysplasia, in which the eruption showed striking sparing of vaccination sites.
泛发性环状肉芽肿(GA)是GA的一种慢性且广泛分布的形式,比局限性类型少见,其原发性丘疹性损害可主要呈环状或非环状排列。已有报道其与包括造血系统恶性肿瘤在内的多种全身性疾病相关。它有明显的同形反应或Koebner现象倾向。我们报告一例极为罕见的与慢性粒单核细胞白血病和骨髓增生异常相关的泛发性非环状GA病例,其中皮疹显著不累及接种部位。