Sterling J C, Marcus R, Burrows N P, Roberts S O
Department of Dermatology, Addenbrooke's Hospital, Cambridge, UK.
Clin Exp Dermatol. 1995 Jan;20(1):73-5. doi: 10.1111/j.1365-2230.1995.tb01291.x.
We describe a middle-aged man with aggressive erythrodermic mycosis fungoides whose responses to several well-established therapies for the disease were either poor or short-lived. Infusion of antibodies engineered against cells expressing the CD4 molecule produced little response. Total body irradiation coupled with autologous bone marrow transplantation led to an encouraging but unfortunately unsustained improvement.
我们描述了一名患有侵袭性红皮病型蕈样肉芽肿的中年男性,他对几种已确立的该疾病治疗方法的反应要么很差,要么持续时间很短。输注针对表达CD4分子的细胞设计的抗体几乎没有产生反应。全身照射联合自体骨髓移植带来了令人鼓舞但不幸未能持续的改善。